Table 3 Comparison of differentially expressed genes between imipenem-selected mutants (this study) and biofilm-associated ATCC 17978 cells as decribed by Rumbo-Feal et al. (12)
From: Transcriptome profiling in imipenem-selected Acinetobacter baumannii
Locus tag | Log2 (fold change) in IPM-2Â m | Log2 (fold change) in IPM-8Â m | Log2 (fold change) biofim vs.expotenetial phase cellsa | Protein Name |
|---|---|---|---|---|
Inverse expressed between imipenem-resistant mutants and biofilm-associated cells | ||||
NameA1S_0087 | -3.76 | -4.52 | 1.36 | Short-chain dehydrogenase/reductase SDR |
A1S_0109 | -3.62 | -6.03 | 5.91 | Homoserine lactone synthase |
A1S_0112 | -1.86 | -4.76 | 6.23 | Acyl-CoA synthetase/AMP-acid ligases II |
A1S_0115 | -2.47 | -5.27 | 7.24 | Amino acid adenylation |
A1S_0116 | -2.97 | -6.01 | 5.81 | RND superfamily transporter |
A1S_0117 | -1.38 | -2.92 | 4.58 | Hypothetical protein A1S_0117 |
A1S_0118 | -2.01 | -4.06 | 3.21 | Hypothetical protein A1S_0118 |
A1S_2214 | -2.40 | -3.86 | 7.49 | CsuD |
A1S_2215 | -3.14 | -4.57 | 7.65 | CsuC |
A1S_2218 | -3.89 | -5.88 | 7.36 | CsuA/B |
Overexpressed both in imipenem-resistant mutants and biofilm-associated cells | ||||
A1S_0538 | 4.48 | 0.39 | 2.72 | RND efflux transporter |
A1S_2534 | 3.34 | 2.02 | 4.40 | Sulfate transport protein |
A1S_0032 | 7.09 | 0.49 | 5.01 | Putative signal peptide |
A1S_2889 | 6.72 | 1.25 | 5.54 | Putative signal peptide |