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Table 1 Correctly detected SVs for simulated data at 20 × coverage under varying levels of heterogeneity

From: SHEAR: sample heterogeneity estimation and assembly by reference

  Deletions Tandem duplications
Variant percent SHEAR IMR/DENOM SHEAR IMR/DENOM
20% 6 / 30 0 / 30 3 / 30 0 / 30
40% 20 / 30 0 / 30 14 / 30 0 / 30
60% 26 / 30 0 / 30 24 / 30 0 / 30
80% 29 / 30 1 / 30 26 / 30 0 / 30
90% 29 / 30 1 / 30 24 / 30 0 / 30
100% 28 / 30 27 / 30 26 / 30 0 / 30
  1. All simulations are done on a 70,000 bp portion of chromosome 15 after introducing deletions and tandem duplications of sizes 150 bp, 1000 bp, and 30,000 bp, each over 10 different iterations, for a total of 30 different deletion events, and 30 different tandem duplication events.