A systematic analysis of protein palmitoylation in Caenorhabditis elegans

BMC Genomics

Table 2 Survival analysis of DHHC and PPT mutant strains

Strain	n	Mean (days)	Median (days)	90% mortality (days)	Maximum (days)
N2	184	20	19	26	28
dhhc-1 (tm4272)	97	17*	18	24^†	27
dhhc-2 (ok990)	100	20	19	26	34
dhhc-9 (gk985)	143	19*	19	24	30
dhhc-12 (gk1013)	50	19	20	26	26
dhhc-12 (gk981)	93	21	21^†	26	28
dhhc-13 (gk36)	93	21	20^†	26	28
dhhc-14 (gk330)	49	18*	18^†	20^†	24
dhhc-14 (ok1032)	48	18*	19	24^†	24
spe-10 (hc104)	95	21	19	29	35
ppt-1 (gk131)	88	21	20	28^†	33
ppt-1 (gk134)	43	19	19	23	28
ppt-1 (gk139)	86	19	19	27	30
ath-1 (ok1735)	80	19	19	24^†	33

Various measures of survival were extracted from lifespan experiments comparing wild-type Bristol N2 and DHHC or PPT mutant strains. Statistical tests were applied to values varying from the control using OASIS [73]. * p < 0.01 by the log-rank (Mantel-Cox) test. ^†p < 0.01 by Fisher’s exact test.

ISSN: 1471-2164