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Table 3 Top 20 genes with largest difference in expression and differential methylation between fetal and adult livers

From: Genetic and epigenetic regulation of gene expression in fetal and adult human livers

Gene Median expression logFC Adj p-value (FDR) Mean beta value Beta value difference Adj p-value (FDR)
Adult Fetal Adult Fetal
DLK1 3.27 12.64 9.15 3.55E-46 0.42 0.63 0.22 3.19E-36
HBZ 3.23 12.35 9.07 1.82E-45 0.8 0.55 -0.25 4.02E-18
HBM 3.01 12.52 9.03 4.27E-42 0.42 0.21 -0.21 2.55E-11
AHSP 4.37 13.26 8.46 2.66E-42 0.74 0.41 -0.33 1.43E-34
EPB42 3.13 11.25 8.19 2.26E-48 0.89 0.47 -0.42 3.84E-64
CYP2E1 13.42 4.1 -7.64 8.63E-36 0.51 0.88 0.36 1.10E-41
HBE1 2.87 10.66 7.63 4.10E-48 0.76 0.49 -0.27 1.41E-34
CRP 13.33 4.33 -7.27 7.71E-34 0.53 0.89 0.36 2.99E-42
C9 11.91 3.59 -7.18 3.98E-39 0.48 0.84 0.36 8.73E-39
APCS 12.69 4.39 -7 5.95E-40 0.45 0.88 0.43 7.26E-48
SLC4A1 4.04 11.3 6.96 1.46E-61 0.75 0.4 -0.35 2.14E-42
NNMT 11.06 3.44 -6.88 4.10E-40 0.36 0.84 0.48 7.10E-45
CYP2C8 12.9 4.83 -6.85 3.42E-31 0.59 0.88 0.29 2.57E-36
AQP9 11.51 3.47 -6.81 1.26E-33 0.39 0.84 0.45 8.23E-45
NFE2 4.1 11.03 6.8 2.29E-47 0.82 0.45 -0.36 3.02E-41
ADH1C 11.93 3.92 -6.69 1.96E-24 0.42 0.81 0.39 8.06E-38
MYL4 3.88 10.77 6.65 6.78E-60 0.88 0.4 -0.48 1.90E-62
C3P1 11.36 3.81 -6.63 2.34E-37 0.73 0.24 -0.49 1.56E-47
RHAG 3.35 10.22 6.56 1.50E-46 0.81 0.49 -0.31 1.64E-47
HSD17B6 12.12 4.61 -6.31 4.88E-29 0.89 0.66 -0.22 1.48E-41