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Figure 2 | BMC Genomics

Figure 2

From: A novel approach for multi-domain and multi-gene family identification provides insights into evolutionary dynamics of disease resistance genes in core eudicot plants

Figure 2

Custom flowchart showing the integrated approach for the identification of conserved multi-domain protein clusters. A bi-directional blast screen between a reference genome and n target genomes marks the entry point to the pipeline (grey box in the upper middle). Grey indicates blast screens. Red indicates filtering steps. White boxes indicate pools of FASTA-formatted sequences. Purple indicates Hidden Markov Modelling steps to predict and map protein domains. Green refers to the CoGe system (see Methods). Ochre indicates custom python scripts. Flowchart starts with two-per-genome bidirectional blast screens (middle) and ends with highly accurate functional protein clusters (black, bottom right).

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BMC Genomics

ISSN: 1471-2164

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