Table 3 Functional areas (GO terms of the categories “cellular component” and “molecular function”) of the genes interacting with miRNAs, i.e., for which a gene versus miRNA interaction has been experimentally shown, sorted for the number of genes included
Functional area | GO term ID | Number of genes | |||
|---|---|---|---|---|---|
Fraction [%] | Observed | Expected | [− log10 p-val] | ||
Cellular component | |||||
Nucleus | GO:0005634 | 23.4 | 688 | 505 | 20.8 |
Cytosol | GO:0005829 | 9.3 | 274 | 205 | 5.1 |
Nucleoplasm | GO:0005654 | 7.4 | 219 | 139 | 10.6 |
Molecular function | |||||
Binding | GO:0005488 | 54.7 | 1612 | 1351 | 34.3 |
Transferase activity, transferring phosphorus-containing groups | GO:0016772 | 5.9 | 174 | 103 | 10.7 |
Transcription factor activity | GO:0003700 | 5.1 | 151 | 84 | 11.6 |