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Table 4 Top 20 Vienna7 vs. wild Hawaiian type differentially regulated genes GO term enrichment

From: A genomic perspective to assessing quality of mass-reared SIT flies used in Mediterranean fruit fly (Ceratitis capitata) eradication in California

Term

Annotated

Significant

Expected

Fisher exact test

p-value

Up-regulated genes

GO:1901360

Organic cyclic compound metabolic processes

1289

130

81.06

6.70E-11

GO:0090304

Nucleic acid metabolic process

948

105

59.61

7.10E-11

GO:0006259

DNA metabolic process

239

42

15.03

3.50E-10

GO:0006725

Cellular aromatic compound metabolism

1231

123

77.41

7.40E-10

GO:0006396

RNA processing

166

33

10.44

1.30E-09

GO:0006139

Nucleobase-containing compound metabolism

1166

117

73.32

2.20E-09

GO:0046483

Heterocycle metabolic process

1212

120

76.21

2.80E-09

GO:0044260

Cellular macromolecule metabolic process

1441

135

90.61

5.50E-09

GO:0090305

Nucleic acid phosphodiester bond hydroly…

78

21

4.9

5.70E-09

GO:0019079

Viral genome replication

13

9

0.82

7.70E-09

GO:0042254

Ribosome biogenesis

60

18

3.77

1.10E-08

GO:0034660

NcRNA metabolic process

74

20

4.65

1.30E-08

GO:0034641

Cellular nitrogen compound metabolic pro…

1291

123

81.18

1.90E-08

GO:0022613

Ribonucleoprotein complex biogenesis

73

19

4.59

5.70E-08

GO:0006260

DNA replication

93

21

5.85

1.60E-07

GO:0044237

Cellular metabolic process

2258

181

141.99

3.90E-07

GO:0019058

Viral infectious cycle

18

9

1.13

4.00E-07

GO:0034470

NcRNA processing

53

15

3.33

4.60E-07

GO:0006807

Nitrogen compound metabolic process

1455

128

91.49

1.30E-06

GO:0006281

DNA repair

82

17

5.16

8.90E-06

Down-regulated genes

    

GO:0048468

Cell development

610

94

42.38

1.30E-15

GO:0048646

Anatomical structure formation

662

95

45.99

9.90E-14

GO:0051239

Regulation of multicellular organismal processes

413

67

28.69

5.00E-12

GO:0030182

Neuron differentiation

331

58

23

7.30E-12

GO:0003008

System process

462

70

32.1

4.20E-11

GO:0030154

Cell differentiation

927

112

64.41

4.60E-11

GO:0009653

Anatomical structure morphogenesis

761

97

52.87

8.80E-11

GO:0048869

Cellular developmental process

964

114

66.98

1.20E-10

GO:0050877

Neurological system process

385

61

26.75

1.60E-10

GO:0048699

Generation of neurons

356

58

24.73

1.60E-10

GO:0007267

Cell-cell signaling

264

48

18.34

1.70E-10

GO:0044767

Single-organism developmental process

1185

131

82.33

2.40E-10

GO:0048513

Organ development

697

90

48.43

2.90E-10

GO:0007423

Sensory organ development

191

39

13.27

3.20E-10

GO:0023052

Signaling

980

114

68.09

3.50E-10

GO:0044700

Single organism signaling

980

114

68.09

3.50E-10

GO:0048749

Compound eye development

122

30

8.48

3.90E-10

GO:0044707

Single-multicellular organism process

1699

169

118.04

4.10E-10

GO:0007154

Cell communication

996

115

69.2

4.50E-10

GO:0042692

Muscle cell differentiation

123

30

8.55

4.80E-10