Term | Annotated | Significant | Expected | Fisher exact test | p-value |
---|---|---|---|---|---|
Up-regulated genes | |||||
GO:1901360 | Organic cyclic compound metabolic processes | 1289 | 130 | 81.06 | 6.70E-11 |
GO:0090304 | Nucleic acid metabolic process | 948 | 105 | 59.61 | 7.10E-11 |
GO:0006259 | DNA metabolic process | 239 | 42 | 15.03 | 3.50E-10 |
GO:0006725 | Cellular aromatic compound metabolism | 1231 | 123 | 77.41 | 7.40E-10 |
GO:0006396 | RNA processing | 166 | 33 | 10.44 | 1.30E-09 |
GO:0006139 | Nucleobase-containing compound metabolism | 1166 | 117 | 73.32 | 2.20E-09 |
GO:0046483 | Heterocycle metabolic process | 1212 | 120 | 76.21 | 2.80E-09 |
GO:0044260 | Cellular macromolecule metabolic process | 1441 | 135 | 90.61 | 5.50E-09 |
GO:0090305 | Nucleic acid phosphodiester bond hydroly… | 78 | 21 | 4.9 | 5.70E-09 |
GO:0019079 | Viral genome replication | 13 | 9 | 0.82 | 7.70E-09 |
GO:0042254 | Ribosome biogenesis | 60 | 18 | 3.77 | 1.10E-08 |
GO:0034660 | NcRNA metabolic process | 74 | 20 | 4.65 | 1.30E-08 |
GO:0034641 | Cellular nitrogen compound metabolic pro… | 1291 | 123 | 81.18 | 1.90E-08 |
GO:0022613 | Ribonucleoprotein complex biogenesis | 73 | 19 | 4.59 | 5.70E-08 |
GO:0006260 | DNA replication | 93 | 21 | 5.85 | 1.60E-07 |
GO:0044237 | Cellular metabolic process | 2258 | 181 | 141.99 | 3.90E-07 |
GO:0019058 | Viral infectious cycle | 18 | 9 | 1.13 | 4.00E-07 |
GO:0034470 | NcRNA processing | 53 | 15 | 3.33 | 4.60E-07 |
GO:0006807 | Nitrogen compound metabolic process | 1455 | 128 | 91.49 | 1.30E-06 |
GO:0006281 | DNA repair | 82 | 17 | 5.16 | 8.90E-06 |
Down-regulated genes | |||||
GO:0048468 | Cell development | 610 | 94 | 42.38 | 1.30E-15 |
GO:0048646 | Anatomical structure formation | 662 | 95 | 45.99 | 9.90E-14 |
GO:0051239 | Regulation of multicellular organismal processes | 413 | 67 | 28.69 | 5.00E-12 |
GO:0030182 | Neuron differentiation | 331 | 58 | 23 | 7.30E-12 |
GO:0003008 | System process | 462 | 70 | 32.1 | 4.20E-11 |
GO:0030154 | Cell differentiation | 927 | 112 | 64.41 | 4.60E-11 |
GO:0009653 | Anatomical structure morphogenesis | 761 | 97 | 52.87 | 8.80E-11 |
GO:0048869 | Cellular developmental process | 964 | 114 | 66.98 | 1.20E-10 |
GO:0050877 | Neurological system process | 385 | 61 | 26.75 | 1.60E-10 |
GO:0048699 | Generation of neurons | 356 | 58 | 24.73 | 1.60E-10 |
GO:0007267 | Cell-cell signaling | 264 | 48 | 18.34 | 1.70E-10 |
GO:0044767 | Single-organism developmental process | 1185 | 131 | 82.33 | 2.40E-10 |
GO:0048513 | Organ development | 697 | 90 | 48.43 | 2.90E-10 |
GO:0007423 | Sensory organ development | 191 | 39 | 13.27 | 3.20E-10 |
GO:0023052 | Signaling | 980 | 114 | 68.09 | 3.50E-10 |
GO:0044700 | Single organism signaling | 980 | 114 | 68.09 | 3.50E-10 |
GO:0048749 | Compound eye development | 122 | 30 | 8.48 | 3.90E-10 |
GO:0044707 | Single-multicellular organism process | 1699 | 169 | 118.04 | 4.10E-10 |
GO:0007154 | Cell communication | 996 | 115 | 69.2 | 4.50E-10 |
GO:0042692 | Muscle cell differentiation | 123 | 30 | 8.55 | 4.80E-10 |