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Table 2 Assessment of the 3D localization of functional annotations in S. cerevisiae

From: Distance-based assessment of the localization of functional annotations in 3D genome reconstructions

Functional annotation

MPED q-values

Contact enrichment q-values

 

HindIII

EcoRI

HindIII

EcoRI

Centromeres

4.0e-04

3.7e-04

2.8e-03

5.6e-03

Long terminal repeats

4.0e-04

3.7e-04

2.8e-03

1.9e-02

Telomeres

0.86 ↓

0.13 ↓

5.0e-02

5.6e-03

  1. MPED: the median of pairwise Euclidean distances in the 3D reconstruction. Contact enrichment: enrichment of dichotomized “close” pairs in the Hi-C contact data. Bold indicates q-value <0.05. Down arrow indicates dispersion (otherwise co-localization). Functional annotations are included if they were significant for both restriction enzyme libraries (HindIII and EcoRI) in either analysis.