From: GWAMAR: Genome-wide assessment of mutations associated with drug resistance in bacteria
drug name | gene id | gene name | mutation | all | h.c. | TGH |
---|---|---|---|---|---|---|
Fluoroquinolones | Rv0006 | gyrA | D94G/A/H/N/Y | Y | Y | 14.1843430424 |
Isoniazid | Rv1908c | katG | S315T/G/N | Y | Y | 9.04507605888 |
Rifampicin | Rv0667 | rpoB | S450L | Y | Y | 8.60191917013 |
Streptomycin | Rv0682 | rpsL | K43R | Y | Y | 8.32303955124 |
Ethambutol | Rv3795 | embB | M306I/V/L | Y | Y | 8.24966301883 |
Isoniazid | Rv1483 | fabG1 | C-15T | Y | Y | 5.8445976648 |
Rifampicin | Rv0667 | rpoB | D435F/V/Y/G/A | Y | Y | 5.0402225732 |
Streptomycin | Rv0682 | rpsL | K88R/M | Y | Y | 4.16354931535 |
Ethambutol | Rv3795 | embB | E504G/D | N | N | 3.33103155053 |
Pyrazinamide | Rv2043c | pncA | W68L | Y | Y | 2.7080502011 |
Pyrazinamide | Rv2043c | pncA | H51P | Y | Y | 2.7080502011 |
Rifampicin | Rv0667 | rpoB | H445D/Y/R | Y | Y | 2.52993515037 |
Streptomycin | Rvnr01 | rrs | G1108C | N | N | 1.71691080314 |
Ethambutol | Rv3795 | embB | D1024N | Y | N | 1.68763546921 |
Ethambutol | Rv3795 | embB | D869G | N | N | 1.68763546921 |
Ethambutol | Rv3795 | embB | A505T | N | N | 1.68763546921 |
Fluoroquinolones | Rv0005 | gyrB | N538T | Y | Y | 1.68478734968 |
Fluoroquinolones | Rv0006 | gyrA | S91P | Y | Y | 1.68478734968 |
Fluoroquinolones | Rv0005 | gyrB | T539I | N | N | 1.68478734968 |
Streptomycin | Rvnr01 | rrs | A1401G | Y | N | 1.28846347057 |