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Table 4 Over half (8) of the overlapped target genes are involved in neurological disease and nervous system function.

From: MicroRNA and messenger RNA profiling reveals new biomarkers and mechanisms for RDX induced neurotoxicity

Category

Function Annotation

P-value

Molecules

# Molecules

Neurological Disease

granular cell tumor

1.98E-03

HMGCR

1

Neurological Disease

Huntington's disease

2.04E-03

BANP, C5ORF13, HMGCR, ROCK2

4

Neurological Disease

subarachnoid hemorrhage

2.98E-03

HMGCR

1

Neurological Disease

neurofibromatosis

6.93E-03

HMGCR

1

Neurological Disease

neurological disorder

1.11E-02

BANP, C5ORF13, HMGCR, LITAF, POLE4, ROCK2

6

Neurological Disease

meningitis

1.68E-02

POLE4

1

Neurological Disease

Charcot-Marie-Tooth disease

2.16E-02

LITAF

1

Neurological Disease

medulloblastoma

3.90E-02

POLE4

1

Neurological Disease

migration of brain cancer cell lines

4.09E-02

C5ORF13

1

Neurological Disease

stroke

4.19E-02

HMGCR

1

Neurological Disease

neuropathy

4.77E-02

HMGCR, LITAF

2

Nervous System Development and Function

morphology of dendritic spines

9.89E-03

ROCK2

1

Nervous System Development and Function

sprouting of neurites

2.07E-02

SULF1

1

Nervous System Development and Function

differentiation of neurons

2.42E-02

C5ORF13, VGF

2

Nervous System Development and Function

retraction of neurites

4.57E-02

ROCK2

1