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Figure 3 | BMC Genomics

Figure 3

From: Mathematical model of the Tat-Rev regulation of HIV-1 replication in an activated cell predicts the existence of oscillatory dynamics in the synthesis of viral components

Figure 3

Kinetics of the viral RNA and proteins synthesized in an activated cell with one provirus copy. А - the abundance of free Tat molecules (not bind to RNA at the TAR element) (blue) and Rev molecules (not bind to 9 kb RNA and 4 kb RNA) (pink) in the nucleus; B - the abundance of free Tat and Rev proteins in the cytoplasm (their kinetics is identical as the corresponding model parameters for these two proteins are identical and the nuclear export of Rev to the cytoplasm is not considered); C - the abundance of 2 kb RNA molecules in the nucleus (blue) and cytoplasm (pink) encoding the Tat and Rev proteins.

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