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Table 1 Estimated mean and standard error of percentage of private mutations for each individual.

From: High burden of private mutations due to explosive human population growth and purifying selection

Group n= 100 n= 492 n= 1000 n= 4299 n= 10000
Constant Population
Size Model
0.995% 0.203% 0.100% 0.023% 0.010%
European History with Two Bottlenecks 1.092% 0.257% 0.129% 0.031% 0.013%
European History with Recent Growth 1.406% 0.750% 0.596% 0.349% 0.237%
NR Data 1.444%
(0.106%)
0.756%
(0.043%)
NA NA NA
ESP Intergenic 2.132% (0.123%) 1.125%
(0.049%)
0.835%
(0.034%)
0.496% (0.019%) NA
ESP Intron 2.233% (0.022%) 1.171%
(0.009%)
0.922%
(0.007%)
0.528%
(0.004%)
NA
ESP Synonymous 2.366%
(0.026%)
1.252%
(0.012%)
0.974%
(0.009%)
0.573%
(0.005%)
NA
ESP UTR 2.492%
(0.079%)
1.305%
(0.034%)
1.004%
(0.025%)
0.596%
(0.014%)
NA
ESP Missense 4.482%
(0.049%)
2.632%
(0.026%)
2.121%
(0.019%)
1.333%
(0.011%)
NA
ESP Nonsense 10.04%
(0.92%)
7.37%
(0.68%)
6.00%
(0.50%)
4.46%
(0.38%)
NA
ESP Splice 14.36%
(2.29%)
10.91%
(1.50%)
8.41%
(1.19%)
6.31%
(0.91%)
NA
  1. The burden of private mutations for n = 100, n = 492, n = 1000, n = 4299 and n = 10000, the corresponding values for Figure 2 and shown here for completeness. The number in parenthesis denotes the standard error across SNVs estimated via bootstrap (Methods). NA indicates that the data for that sample size is not available in the respective dataset.
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