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Table 1 Sensitivity and PPV comparison between methods on datasets simulated assuming uniform, respectively geometric expression of transcripts, with reads length 400 bp, mean fragment length 450 bp and 10% standard deviation.

From: Transcriptome assembly and quantification from Ion Torrent RNA-Seq data

Transcript expression

Methods

# assembled transcripts

# confirmed annotated transcripts

Sensitivity (%)

PPV (%)

Uniform

Cufflinks

18,582

12,909

51.06

69.47

 

MaLTA

23,706

18,698

76.69

78.87

 

IsoLasso

21,441

15,693

63.52

73.19

Geometric

Cufflinks

17,377

12,449

50.21

71.64

 

MaLTA

22,931

18,293

76.05

79.77

 

IsoLasso

20,816

15,308

62.83

73.54