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Table 6 Comparisons of ARB, SMM-align, CombLib, MHC2SK, NN-algin and MHC2MIL on DP and DQ. For each allele, the largest value is displayed in boldface.

From: MHC2MIL: a novel multiple instance learning based method for MHC-II peptide binding prediction by considering peptide flanking region and residue positions

allele ARB SMM-align CombLib MHC2SK NN-align MHC2MIL
HLA-DPA1_01-DPB1_0401 0.746 0.767 0.704 0.778 0.802 0.791
HLA-DPA1_0103-DPB1_0201 0.745 0.767 0.724 0.789 0.793 0.808
HLA-DPA1_0201-DPB1_0101 0.743 0.786 0.723 0.824 0.818 0.834
HLA-DPA1_0201-DPB1_0501 0.709 0.728 0.729 0.794 0.787 0.805
HLA-DPA1_0301-DPB1_0402 0.771 0.818 0.756 0.838 0.828 0.846
HLA-DPB1_0301-DPB1_0401 - - - 0.792 - 0.790
HLA-DQA1_0101-DQB1_0501 0.741 0.783 0.728 0.789 0.805 0.781
HLA-DQA1_0102-DQB1_0602 0.708 0.734 0.752 0.770 0.762 0.769
HLA-DQA1_0301-DQB1_0302 0.637 0.663 0.616 0.676 0.693 0.706
HLA-DQA1_0401-DQB1_0402 0.643 0.761 0.637 0.767 0.742 0.774
HLA-DQA1_0501-DQB1_0201 0.700 0.736 0.620 0.775 0.777 0.810
HLA-DQA1_0501-DQB1_0301 0.756 0.801 0.745 0.807 0.811 0.817
average AUC 0.718 0.759 0.703 0.783 0.783 0.794