Table 1 Identified exon modules display distinct functional profiles
Module | Top Enriched Go Terms(pval<1e-3) | Interacting Genes (pval<1e-3) | Top Regulators | Top Targets (non-RBPs) |
|---|---|---|---|---|
1 | instal larval or pupal morphogenesis, metamorphosis, post-embryonic morphogenesis | DP, hp, Rbf, slpr, Myd88 | Fib:2, CG6995:19, eIF-4a:6, sm:3, CG17838 | CG17273:3, CSN3:4, CG9797:2, Abi:4, Akap200:5 |
2 | organ development, instar larval or pupal development, post-embryonic morphogenesis | fz2, E2f, hop, hep, dco | Rbp2:3, Patr-1:3, dom:4, pum:3 CG7185:6 | Trf2:4, CG3662:4, CG2943:7, Arf51F:4, CG2947:5 |
3 | regulation of cellular process, organ development, generation of neurons | Su(H), Notch, mew, E2f, mys | (2)d:5 gw:52, CG30122:7 CG4119:3 Sxl:15 | CG8116:2, CG42551:3, CG9132:2, Spt6:3, Gprk1:12 |
4 | organ development, locomotion, neuron di_erentiation | Pc, mew, hop, ph-d, w | CG11266:4 su(w[a]):6 Dcp2:4, Zn72D:4, Psi:3 | RhoGAP71E:5, CG4699:10, prod:2, Abl:6, l(1)G0232:6 |
5 | organ morphogenesis, sensory organ development, epithelium development | rux, Pvf1, sli, Egfr, CycB | me31B:3, msi:6, CG11133, spn-E, xmas-2 | CG12424:5, CG16791:13, tutl:6, LanB2:8, CG3907:3 |
6 | regulation of primary metabolic process, regulation of biosynthetic process, regulation of gene expression | trx, w, Pc, arm, mor | CG6995:14 CG1646:10 Psi:5, brm:5, qkr58E-2:4 | CG1244:10, CG42245:5, Syb:2 slmb:4, CG42614:12 |
7 | imaginal disc development, wing disc morphogenesis, post-embryonic appendage morphogenesis | wupA, fz2, NiPp1, Tm2, Prm | CG34362:8, CG13124:10, shot:6, CG3209:4 CG8547:5 | stv:8, CG15105:6, CG15105:9, CG34398:13, CG13188:6 |
8 | Â | Rac1, Rac2 | Smg6:5, Chd1:2, snRNA:U5:38ABb, snRNA:U5:14B, snRNA:U5:23D | gammaCop:6, Nat1:2 Cip4:8, sec24:4, Utx:11 |
9 | sarcomere, myo_bril, tissue development | Mhc, Dp, arm, l(2)gl, Rbf | Sxl:14, AGO1:6, Nop56:2, CG6209, SF2:3 | CG42783:7, lqf:12, Zasp:10, CG42446:4, CG7188:2 |
10 | Â | Rho1, Pvf1, Taf1, Egfr, Ras85D | CG13124:7, CG4266:2, CG3558:4 | CG15609:7, CG8677:4, CG2991:5, RhoGEF2:21, Pen:4 |
Network | anatomical structure morphogenesis, system development, protein-binding, multicellular organismal development | Sb, Rho1, Pc, mew, baz | CG30122:7, (2)d:5, pUf68:5, CG4119:3, gw:52 | stv:8, psq:17, CG8116:2, l(1)G0232:6, trx:17 |