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Figure 4 | BMC Genomics

Figure 4

From: Properly defining the targets of a transcription factor significantly improves the computational identification of cooperative transcription factor pairs in yeast

Figure 4

Robustness analysis of the fourth proposed algorithm (PA4). The average rank of our PA4 when using (a) 10-25, (b) 10-20 and (c) 10-10 as the p-value thresholds for determining the number of the reported predicted cooperative TF pairs (PCTFPs), which is (a) 22, (b) 33 and (c) 88, respectively. It can be seen that the PCTFPs from our PA4 are always more biologically meaningful than those from the 12 existing algorithms since our PA4 always has the smallest average rank no matter which p-value threshold is used. This suggests that our PA4 is robust against different p-value thresholds.

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