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Figure 3 | BMC Genomics

Figure 3

From: Integrated analyses to reconstruct microRNA-mediated regulatory networks in mouse liver using high-throughput profiling

Figure 3

UPmiRs regulatory network. This network involves 536 interactions between 33 UPmiRs and 204 DEGs. Fifteen of the 48 UPmiRs did not have known validated targets (Table 2). The regulator hub-UPmiR is miR-381-3p which has 45 target genes (Table S3.1). Down-regulated Nfib being targeted by 12 UPmiRs (Table S3.2) is the miRNA target hub. The background of hub-miRNAs/genes is marked in purple. The V-shaped nodes correspond to the miRNAs, while the rectangle-shaped nodes are the target genes. The up-regulated miRNAs/genes are marked in red; down-regulated miRNAs/genes are marked in green. Regulatory effects are illustrated as blunt ends () between miRNAs and genes.

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