Integrated analyses to reconstruct microRNA-mediated regulatory networks in mouse liver using high-throughput profiling

Table 2 Statistics for curated miRNA-target interactions.

	miRNA	Number of curated targets	Number of DE miRNA target genes in *Mir122a*^-/-mice
	miR-429-3p	438	39
	miR-200a-3p	394	25
	miR-200b-3p	410	25
	miR-200c-3p	382	26
	miR-182-5p	379	18
	miR-326-3p	175	16
	miR-199a-5p	249	24
	miR-673-3p	0	0
	miR-337-3p	36	2
	miR-337-5p	0	0
	miR-540-3p	0	0
	miR-431-5p	178	5
	miR-127-3p	39	1
	miR-127-5p	1	0
	miR-434-3p	7	0
	miR-434-5p	23	2
	miR-136-3p	0	0
	miR-136-5p	501	24
	miR-379-5p	138	6
	miR-379-3p	0	0
	miR-411-3p	26	2
	miR-411-5p	140	15
	miR-299a-5p	18	1
Up-regulated	miR-329-3p	329	5
	miR-494-3p	427	26
	miR-1193-3p	0	0
	miR-543-3p	480	36
	miR-495-3p	644	40
	miR-376c-3p	337	18
	miR-376b-3p	227	10
	miR-376b-5p	0	0
	miR-376a-3p	11	1
	miR-300-3p	40	6
	miR-381-3p	606	45
	miR-382-5p	296	20
	miR-382-3p	1	0
	miR-134-5p	203	14
	miR-485-5p	140	9
	miR-485-3p	0	0
	miR-154-3p	0	0
	miR-154-5p	226	11
	miR-496a-3p	218	13
	miR-541-5p	298	20
	miR-409-5p	0	0
	miR-409-3p	29	2
	miR-369-3p	0	0
	miR-369-5p	0	0
	miR-410-3p	524	29
Down-regulated	miR-455-3p	3	0
	miR-455-5p	0	0
	miR-31-3p	0	0
	miR-31-5p	334	36
	miR-93-5p	705	83
	miR-339-3p	0	0
	miR-335-5p	223	19
	miR-486b-5p	28	2
	miR-144-3p	709	72
	miR-451a	108	31
	miR-345-5p	18	5
	miR-17-5p	992	115
	miR-19a-3p	602	62
	miR-484	0	0
	miR-802-5p	0	0
	miR-145a-5p	262	26
	miR-322-5p	817	80
Total	65 DemiRs^a	4,220^b*	499^c,*

^a includes 48 up-regulated miRNAs and 17 down-regulated miRNAs
^b includes 460 up-regulated target genes and 263 down-regulated target genes, for a total of 723 genes.
^c includes 295 up-regulated genes and 204 down-regulated genes of the 886 differentially-expressed genes found in 2-month old Mir122a-/- mouse livers [32].
* indicates the unique gene count

ISSN: 1471-2164