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Table 7 Class-wise statistics on the number of enzyme sequences, and the subclasses at each level.

From: Application of a hierarchical enzyme classification method reveals the role of gut microbiome in human metabolism

EC Level-1(6 Classes)
(Example:1.x.x.x)
Total Sequences Subclasses at
EC Level-2 (example:1.1.x.x)
Subclasses at
EC Level-3 (example:1.1.1.x)
Subclasses at
EC Level-4 (example:1.1.1.1)
EC1: Oxidoreductases 8662 22 90 658
EC2: Transferases 23604 9 31 751
EC3: Hydrolases 15183 11 49 781
EC4: Lyases 5525 7 15 268
EC5: Isomerases 4146 6 17 127
EC6: Ligases 7830 6 11 109
Total 64950 61 213 2693
  1. There are 6 major classes at Level-1 that expand into 61, 213 and 2,693 subclasses at Levels 2, 3 and 4, respectively.