Table 2 Occurrence of MAP kinases signalling pathway genes in the studied breast tissue/cell signatures.
Gene Symbol | In obesity signature? (Yes/No) | In IGF1 signature? (Yes/No) | Number of reference signatures containing gene (out of 70) | Statistically novel (SN) or common (SC) |
|---|---|---|---|---|
ATF2 | Y | N | 0 | SN |
DUSP8 | N | Y | 0 | SN |
GADD45G | Y | N | 0 | SN |
HRAS | N | Y | 0 | SN |
IKBKB | Y | N | 0 | SN |
MAP4K3 | Y | N | 0 | SN |
MAPK9 | N | Y | 0 | SN |
MAPKAPK5 | N | Y | 0 | SN |
MAX | Y | N | 0 | SN |
PPM1B | Y | N | 0 | SN |
PPP3R1 | N | Y | 0 | SN |
RAPGEF2 | Y | N | 0 | SN |
RPS6KA4 | N | Y | 0 | SN |
SOS1 | Y | N | 0 | SN |
CHUK | N | Y | 1 | SN |
FGF13 | N | Y | 1 | SN |
FGFR2 | N | Y | 1 | SN |
MAP2K6 | N | Y | 1 | SN |
PAK2 | Y | N | 1 | SN |
RASA1 | Y | N | 1 | SN |
RPS6KA3 | N | Y | 1 | SN |
DDIT3 | N | Y | 2 | SN |
FLNA | N | Y | 2 | SN |
IL1R1 | N | Y | 2 | SN |
MAP2K4 | Y | N | 2 | SN |
FGFR4 | Y | N | 3 | SN |
DUSP5 | N | Y | 4 | SC |
MAP3K8 | N | Y | 4 | SC |
DUSP6 | Y | Y | 8 | SC |
FOS | N | Y | 8 | SC |
DUSP4 | Y | Y | 12 | SC |