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Figure 1 | BMC Genomics

Figure 1

From: TMC and EVER genes belong to a larger novel family, the TMC gene family encoding transmembrane proteins

Figure 1

The murine TMC protein family Murine (Mm) TMC amino acid sequences were aligned using the MultAlin sequence comparison algorithm. Positions that are conserved (identical or similar) in all three subfamilies are marked orange (present in at least 4 of the 8 sequences) and red (conserved in at least 6 of the 8 sequences). Conserved positions within individual TMC protein subfamilies are depicted in blue. Amino acids that were considered similar based on the physicochemical features of their side chains: L, I, V and M; F and Y; E, D, N and Q; T and S; K and R. The TMC motif is denoted with a green bar. Presumptive transmembrane regions are underlined. Indicated with bold letters is experimentally verified TMC sequence.

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BMC Genomics

ISSN: 1471-2164

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