Figure 3

Neighbour-joining tree illustrating the relationship between representative insect and mammalian GST classes. GSTs from the non-insect specific classes from A. gambiae, D. melanogaster were aligned with representatives from mammalian classes using ClustalW. The tree was constructed by the neighbour-joining method from a similarity matrix of pairwise comparisons made using the Jukes-Cantor algorithm. Sequences shown in blue are from A. gambiae. Dm = D. melanogaster, Hs = Homo sapiens, Rn = Rattus norvegicus. Nodes with distance bootstrap values (500 replicates) of > 70% are marked by*.