Table 4 Pathologs related to other disorders. Representative disease is shown for each clone. *RTPS6.3 (representative transcript protein set 6.3) cluster representative transcriptional unit (TU) of the FANTOM2 clone set. OMIM status: 1 = gene present in OMIM with a reported disease; 2 = gene present in OMIM with different disease association or without disease; 3 = gene not present in OMIM.

IMMUNOLOGICAL

    Diagnosis

1500019E10*

AK005285

Replication protein a 14 kda subunit

Systemic lupus erythematosus

1

1810019E15

AK007546

Dek protein

LES and Juvenile RA

2

2700059D02*

AK012454

Uveal autoantigen

Behecet's Disease, sarcoidosis and Vogt-Koyanagi-Harada disease

3

4632415P04*

AK028516

Golgi complex autoantigen golgin-97

Sjogren's syndrome

1

D030032G01*

AK050903

Neuroblast differentiation associated protein ahnak

Systemic lupus erythematosus

2

    Pathophysiology

A630006E02*

AK041380

Minor histocompatibility antigen ha-1

Graft-versus-host disease

1

B230303A05*

AK045681

U1 small nuclear ribonucleoprotein c

Autoimmunity to U1 snrnps

1

B230397K24*

AK046480

L1 retroposon, orf2 mrna

Rheumatoid arthritis

3

C330006A15*

AK049133

Ribonuclease p protein subunit p38

Scleroderma autoimmune antigens

1

F830032C23*

AK089843

Caspase recruitment domain protein 15

Crohn's disease

1

NEUROLOGICAL

    Pathophysiology

2210420D18

Serine/threonine kinase rick

Alzheimer's disease

2

4833420A15

AK014731

Huntingtin-interacting protein-1 protein interactor

Huntington's disease

1

9330170I02*

AK034263

Metabotropic glutamate receptor 2 precursor

Alzheimer's disease

2

B230307E07

AK045716

Excitatory amino acid transporter 1

Alzheimer's disease

3

CARDIOVASCULAR

    Pathophysiology

1700127D06*

AK007298

Tisuee kallilrein

Hypertension

1

2510048K03*

AK011112

Prolylcarboxypeptidase

Essential hypertension

1

4833405G23

AK029362

Rtp801-like protein

Ischemic diseases

3

9630044I02

AK036182

Mitochondrial isoleucine trna synthetase

Cardiomyopathy

3

B430208E24*

AK046620

Ras gtpase-activating Protein 1

Neuropathology of ischemia

2

D130064D17*

AK051677

Lysosomal pro-x carboxypeptidase precursor

Essential hypertension

3

E030024D09*

AK087056

Angiotensin converting enzyme

Hypertension

1

2310063B19*

AK010021

Epoxide hydrolase

Hhypertension

2

REPRODUCTIVE

    Pathophysiology

0610007H07*

Z-protein

Fetal loss

3

1700010P14*

AK005852

Nyd-sp6

Spermatogenesis

3

4631410O16*

AK028461

Sumo-1-specific protease 1

Reproduction

1

4930406H24*

AK029590

Adam 26 precursor

Spermatogenesis

3

B130010I06*

AK044891

Dmrt2/terra-like protein

Sex differentiation disorders

3

D030049L20

AK050982

Sperm antigen

Immunologic infertility

1

OTHERS

    Pathophysiology

1110004H01*

AK003421

Mitochondrial import inner membrane translocase subunit tim9 b

Fracture healing

3

1810015E19

AK007508

Slp-1

Autism

1

1810015M19*

AK019013

Lw glycoprotein

Sickle cell disease

1

4932434G09*

AK016547

Ribonucleases p/mrp protein subunit pop1

Connective tissue diseases

3

5730465G20

AK077598

N-acetyllactosaminide beta-1,6-n-acetylglucosaminyl Transferase

Blood group I gene

3

9830131G07*

AK036537

Bomapin

Hematopoiesis

2

9930031F20

AK036967

Vp165

Type 2 diabetes

3

A130042M24*

AK037730

Mucin

COPD

1

A730076H11

AK043253

T-cell receptor alpha chain precursor v-j region

Leishmania major

3

A830007N20

AK043557

Wd-repeat protein 3

Triple-A syndrome

1

B830002B15*

AK046772

Polycystic kidney disease 2-like protein

Cystic diseases

1

C230099M23*

AK082743

Vesicular glutamate transporter 2

Schizophrenia

3

E130216C05

AK087459

Amyloid beta precursor-like protein 2

Healing corneal epithelium

2

    Treatment

5033405N08*

AK017155

Agmatinase

Chronic pain, addictive states and brain injury

3

A930028N13

AK044634

Ankyrin-2

Human hemolytic anemias

2