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Table 1 Quantitative performance comparisons for myristoylation prediction algorithms. Each model was evaluated using the same test set, consisting of 80 positive and 185 negative plant sequences. For the Expasy algorithm, only 183 negative sequences could be analyzed because two contained "X" characters (denoting ambiguous amino acids), which the program was unable to process. Abbreviations: TP, true positives; FN, false negatives; FP, false positives; TN, true negatives. Names in parentheses after each HMM indicate the sequence weighting scheme used to build the model.

From: Predicting N-terminal myristoylation sites in plant proteins

Model Name Threshold Cutoff Number Correct TP FN FP TN Accuracy (TP+TN)/TOTAL Coverage TP/(TP+FN)
Prosite (nominal) 238 64 16 11 174 89.8% 80.0%
NMT -2.75 252 70 10 3 182 95.1% 87.5%
NMT 0.00 233 51 29 3 182 87.9% 63.8%
BGM 1.85 248 77 3 14 171 93.6% 96.3%
BGM 0.00 236 79 1 28 157 89.1% 98.8%
Expasy 0.89 244 62 18 1 182 92.8% 77.5%
Expasy 0.85 241 62 18 4 179 91.6% 77.5%
Expasy 0.40 220 66 14 29 154 83.7% 82.5%
HMM80 (Gerstein) 2.05 265 80 0 0 185 100.0% 100.0%
HMM80H (Henikoff) 1.55 265 80 0 0 185 100.0% 100.0%
HMM80V (Voronoi) 1.75 265 80 0 0 185 100.0% 100.0%