| | Between strains | Within strains |
|---|
| | MA-ANOVA | Hierarchical t-test |
|---|
| | | CBA | BL10 | BL6 | DBA | BALB |
|---|
Correlation | | 0.95 | 0.95 | 0.87 | 0.87 | 0.92 |
|---|
Naive (p < 0.05) | 718 | 737 | 610 | 963 | 1043 | 483 |
Bonferroni | 0 | 2 | 4 | 1 | 0 | 3 |
FDR 10% | 88 | 2 | 4 | 14 | 0 | 16 |
- Correlation between two individuals per strain was calculated using Pearson's correlation coefficient. Significance levels (p-values) between strains were calculated with MA-ANOVA, and within strains using the hierarchical t-test. Differential gene expression was determined by selecting genes with p-values lower than a specified threshold. Thresholds were selected using three different strategies; naive, Bonferroni corrected, and False Discovery Rate (10%), and resulted in different numbers of significantly differentially expressed genes.
