cDNA array-CGH profiling identifies genomic alterations specific to stage and MYCN-amplification in neuroblastoma

Table 2 Recurrent regions related to MYCN status and stage

	Imbalance	Chr.	Cytoband	Start (Mb)	End (Mb)	Clone No.
Common to 1, 4-, & 4+	gain	7	7q32	133.19	137.05	26
	gain	17	17q21	42.13	53.53	157
	gain	17	17q23	55.41	61.8	99
	gain	17	17q24	65.59	73.44	70
	loss	3	3p21	45.72	46.77	13
Shared by 1 & 4-	gain	7	7p14	32.41	32.83	11
	gain	7	7q11	69.89	72.34	28
	gain	7	7q36	148.74	152.97	39
	gain	17	17q12	35.45	36.41	15
	gain	17	17q21	39.56	40.03	16
Specific to 1	gain	2	2p22	32.23	33.33	12
	gain	17	17p13	2.12	2.59	11
	gain	17	17p13	5.67	7.17	22
	gain	17	17p13	8.23	9.42	17
	loss	8	8p12	38.32	39.84	12
	loss	8	8q22-23	109.54	116.64	13
	loss	11	11q12	60.87	63.09	29
	loss	14	14q12	28.94	31.32	11
	loss	14	14q23	58.04	58.76	12
	loss	19	19q13	43.4	44.05	13
Specific to 4-	gain	7	7p15	24.26	25.89	12
	gain	7	7q34	139.53	141.16	22
	loss	11	11q21	96.25	96.83	11
	loss	11	11q22	108.12	110.64	11
	loss	11	11q23	114.31	120.39	51
	loss	11	11q24	125.28	126.76	20
	loss	11	11q25	131.98	134.08	19
Specific to 4+	gain	2	2p24-25	10.97	20.08	38
	loss	1	1p36	6.16	13.42	78
	loss	1	1p36	15.22	16.13	20

ISSN: 1471-2164