Distributions of liver/brain RQ ratios for all amplification methods. Box and whiskers plot showing the distribution of log2 RQ ratios for each amplification method. The blue diamond is centered on the mean and shows the 95% CI of the mean. The blue lines depict the percentile range. The center of the notched box is the median, with the notches showing the 95% CI of the median. The boxes show the inter-quartile range (IQR). Dashed lines are 1.5 times the IQR. Outliers are shown as red crosses (1.5–3.0 times the IQR) or red circles (>3.0 times the IQR).