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Table 3 Examples of modules of shared cis-elements found in highly expressed genes in 3 immune tissues. Elements were clustered with at least 2 other cis-elements within a 200 bp window, indicating the presence of a putative regulatory module which contained at least 3 transcription factor binding sites, one of which was required to be a lymphoid element. All are located within 3 kb upstream and 100 bp downstream of the first bp of exon 1. The modules were present in the mouse and human orthologs of at least 2 genes from sets of genes that were highly expressed in thymus, stimulated lymph nodes, or activated T-cells. The number of genes for which orthologs were available: thymus, 7; lymph node, 4; activated T-cells, 17.

From: Microarray and comparative genomics-based identification of genes and gene regulatory regions of the mouse immune system

Thymus Stimulated Lymph Node Activated T-cell
MAZF SP1F ZBPF AP2F CDEF EGRF SP1F ZBPF ZF5F MAZF SP1F ZBPF
EGRF MAZF SP1F ZBPF LHXF NKXH OCT1 RBIT CREB SP1F ZBPF
ETSF SP1F ZBPF EGRF ETSF NFKB E2FF MAZF SP1F
AP2F EGRF HESF MAZF SP1F ZBPF GATA HOXF NKXH ECAT PCAT SP1F ZBPF
ETSF MAZF SP1F STAT ZBPF LHXF NKXH OCT1 ETSF MAZF MZF1
AP2F EGRF ETSF SP1F ZBPF NKXH OCT1 RBIT EGRF SP1F ZBPF
EGRF MAZF P53F SP1F   IKRS MAZF NFKB
GATA HAML MYT1   E2FF EBOX ETSF MAZF SP1F ZF5F
   BCL6 CREB E2FF STAT
   HOXF LEFF LHXF OCT1
   MAZF MZF1 NFKB PAX5