Figure 6

(a) Hierarchical clustering of high-affinity NF-κB DNA-binding sites. The probability over 100 bp intervals for finding a high-affinity NF-κB-binding site was used for hierarchical clustering (data from Table I) of the early and late NF-κB dependent gene promoters. Data is shown as a heat map, where green = 0, red = 1. The common name of each gene is shown at right. Note that there is no separation of early and late gene promoters based on the pattern or location of the NF-κB-binding sites. (b) Co-occurrence of high-affinity NF-κB- and AP-1 DNA-binding sites. Superimposed on the NF-κB binding site analysis is the presence and location of high-affinity AP-1 DNA-binding sites. The location of each AP-1 DNA-binding site is indicated in black.