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Table 1 Nucleotide substitution rate. Nucleotide substitution rates for SNPs in promoter regions (P) and all SNPs genomewide (A) show roughly similar rates for transition and transversion substitution, with a slight increase in CG transversions as would be expected from CG rich regions.

From: The distribution of SNPs in human gene regulatory regions

Type Substitution Frequency (P) Frequency (A)
Purine A ↔ G 31.55% 33.10%
Pyrimidine C ↔ T 30.99% 33.10%
Purine ↔ Pyrimidine C ↔ G 12.75% 8.93%
Purine ↔ Pyrimidine A ↔ C 9.43% 8.77%
Purine ↔ Pyrimidine G ↔ T 9.33% 8.82%
Purine ↔ Pyrimidine A ↔ T 5.94% 7.42%