Table 1 Nucleotide substitution rate. Nucleotide substitution rates for SNPs in promoter regions (P) and all SNPs genomewide (A) show roughly similar rates for transition and transversion substitution, with a slight increase in CG transversions as would be expected from CG rich regions.
From: The distribution of SNPs in human gene regulatory regions
Type | Substitution | Frequency (P) | Frequency (A) |
|---|---|---|---|
Purine | A ↔ G | 31.55% | 33.10% |
Pyrimidine | C ↔ T | 30.99% | 33.10% |
Purine ↔ Pyrimidine | C ↔ G | 12.75% | 8.93% |
Purine ↔ Pyrimidine | A ↔ C | 9.43% | 8.77% |
Purine ↔ Pyrimidine | G ↔ T | 9.33% | 8.82% |
Purine ↔ Pyrimidine | A ↔ T | 5.94% | 7.42% |