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Table 2 Transcription factor binding site sequence similarity. Examples of the three classes of degeneracy in binding site sequence motifs. For motif pairs with exact coverage, the less restrictive motifs were used. Motif pairs in the partial coverage and single difference categories were merged into a composite motif.

From: The distribution of SNPs in human gene regulatory regions

Category

Pair Number

Binding Site Examples

  

Sequence

Site Name

Exact Coverage

310

YYCCGCCC

CCCCGCCC

EARLY-SEQ1

(Sp1)-TK.1

Partial Coverage

1,114

TGGNNNNNNGCCA

YTGGCANNNTGCCAR

NFI_CS3

TGGCA_RS

Single Difference

833

TKCTGATTGTYTMM

TKCTGATTGGYTMM

E-alpha_Y_box

NF-Y_CS