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Table 2 Fold change of induced gene expression in B lymphoblasts treated with ionophore A23187. Genes listed here showed a 2-fold increase or more in gene expression in at least one of the three B lymphoblasts cultured for 48 h with 200 nM A23187. Data are fold changes calculated from hybridization values in treated versus non treated cells for each one of the B lymphoblasts respectively (see additional file 1). For each functional group, the genes were ordered by using a program for gene clustering. *Genes basally expressed differently in the cell lines (see additional file 2).

From: Identification of genes involved in Ca2+ ionophore A23187-mediated apoptosis and demonstration of a high susceptibility for transcriptional repression of cell cycle genes in B lymphoblasts from a patient with Scott syndrome

Accession no. control daughter's Scott Gene definition
     Chemokines
D90144 2.05 2.79 1.80 LD78 alpha
M26383 12.28 15.78 8.70 MONAP
D43768 11.58 30.28 11.87 SCM-1*
NM002984 5.46 8.43 4.63 SCYA4
U83171 9.70 2.44 2.29 macrophage-derived chemokine*
U02020 3.79 4.71 3.37 PBEF
X13274 4.19 3.20 9.17 IFN-gamma
D12614 2.83 3.91 3.01 TNF-beta
     Cell proliferation
AB044548 7.36 1.83 1.77 P/OKcl.6*
X79067 2.40 1.98 1.56 ERF-1
X59892 4.29 4.83 4.71 IFN-inducible gamma 2
AB021663 7.95 12.89 5.23 leucine-zipper protein
D84224 7.47 10.92 7.44 methionyl tRNA synthetase
X52560 4.32 4.10 3.70 NF-IL6
AF064105 3.44 3.00 2.67 Cdc14B3 phosphatase
AF022375 2.86 2.22 2.63 VEGF
X77366 2.66 2.51 2.42 HBZ17
M91196 2.02 3.70 3.47 DNA-binding protein
J04076 3.67 3.88 3.41 EGR2
U09587 2.01 2.13 2.20 glycyl-tRNA synthetase
U12767 3.84 4.00 7.02 MINOR
U27655 3.70 1.76 3.60 RGP3
U88964 -1.14 1.14 2.57 HEM45*
D87116 1.67 1.79 2.71 MAP kinase kinase 3b
     Metabolism
U08997 2.03 2.41 1.82 glutamate dehydrogenase
X01630 12.51 17.87 15.17 argininosuccinate synthetase
M55543 6.11 4.96 4.47 GPB-2*
M37721 2.20 2.27 2.77 peptidylglycine alpha-amidating monooxygenase
AF081195 2.48 3.98 2.18 CalDAG-GEFII
U53347 2.05 2.21 2.25 neutral amino acid transporter B
M77836 2.86 3.08 2.36 pyrroline 5-carboxylate reductase
X05908 2.18 3.45 2.77 Lipocortin*
X92720 2.05 2.10 2.34 phosphoenolpyruvate carboxykinase
AK000379 2.82 2.91 3.10 similar to asparagine synthetase
X76488 2.43 2.48 2.44 lysosomal acid lipase*
S52784 3.36 3.86 4.85 cystathionine gamma-lyase
U26398 1.98 3.69 2.77 inositol polyphosphate 4-phosphatase
AF002020 1.03 1.33 3.00 Niemann-Pick C disease protein
M11233 1.23 1.21 3.59 cathepsin D*
     Metallothionein family
M13003 2.85 10.83 1.90 metallothionein-I F*
K01383 3.62 4.60 3.90 metallothionein-I A
D13365 2.74 2.46 2.36 GIF
X64177 1.91 2.79 1.82 metallothionein
M10942 1.93 2.49 2.17 metallothionein-I E
     Micellaneous
M31516 5.63 4.00 3.57 decay-accelerating factor
D90224 4.84 3.93 2.16 GP 34*
M27492 2.28 3.60 3.07 IL-1 receptor*
AF104032 2.43 3.06 2.83 LAT1
X03444 2.79 2.02 3.66 lamin A*
U33017 1.90 2.62 1.56 SLAM
U16954 1.97 2.35 2.81 AF1q*
U64863 4.14 4.57 3.41 PD-1*
Y14039 2.25 3.48 2.51 CASH alpha*
U76248 2.47 2.81 2.68 SIAH2
M80899 2.13 1.33 2.69 AHNAK*