Multiple sequence alignment of the nucleotide sequences flanking the insertion sites of copies of the SR3 non-LTR retrotransposon within the genome of Schistosoma mansoni. Sequences flanking the 5'UTR of SR3-left and SR3-right are aligned in the top panel, while those flanking the 3'-terminus of SR3-left and SR3-right are presented in the bottom panel. Target site duplications are evident at the sites of SR3-left and SR3-right integration, and are indicated with bold font. Conservation of residues is indicated by the shading of boxes. Target sequences were identified among entries in the GSS database of S. mansoni sequences at GenBank or the Sanger Institute [39, 40].