Analysis of vertebrate genomes suggests a new model for clade B serpin evolution

BMC Genomics

Table 2 Intron/exon phasing in vertebrate clade B serpin genes

Species	Gene¹	A²	C³	E
D. rerio	B1	UTR	NP	1
T. nigroviridis ^† T. rubripes ^†	B1	UTR	NP	1
X. tropicalis	B1	UTR	NP	1
	B5	UTR	NP	1
	B6	UTR	NP	1
	B12	UTR	NP	1
G. gallus	B1	UTR	NP	1
	B2	UTR	0	1
	B5	UTR	NP	1
	B6	UTR	NP	1
	B10a	UTR	*	1
	B10b	UTR	0	1
	B12	UTR	0	1
	B14	UTR	0	1
	B14b	UTR	0	1
	B14c	UTR	0	1
H. Sapiens	B1	UTR	NP	1
	B2	UTR	0	1
	B3/4	UTR	0	1
	B5	UTR	NP	1
	B6	UTR	NP	1
	B7	UTR	0	1
	B8	UTR	NP	1
	B9	UTR	NP	1
	B10	UTR	0	1
	B11	UTR	0	1
	B12	UTR	0	1
	B13	UTR	0	1

¹ Gene names are given without the Serpin root.
² UTR = intron occurs in the 5' untranslated region and thus has no phase
³ NP = Intron not present, * = Intron cannot be reliably predicted and no EST exists.
^† Intron phasing predicted from consensus sequence

ISSN: 1471-2164