Table 4 Putative apoptotic mediators absent in S. cerevisiae
From: Comparative analysis of programmed cell death pathways in filamentous fungi
Protein/Domain | ASP | SOR | Scer | Spom | BAS | Biological function/process |
|---|---|---|---|---|---|---|
TRAF-3 | 1 | 1 | 0 | 0 | 1 | Caspase dependent apoptosis |
Mst3/STK24 | 1 | 0–1 | 0 | 2 | 0–1 | Caspase dependent apoptosis |
PARP | 1 | 1 | 0 | 0 | 0 | Caspase independent apoptosis |
AMID | 1–2 | 0–1 | 0 | 0 | 1 | Caspase independent apoptosis |
GRIM-19 | 1 | 1 | 0 | 0 | 1–2 | Electron transport, NADH ubiquinone oxidoreductase |
NDUFS1 | 1 | 1 | 0 | 0 | 1 | Electron transport, NADH ubiquinone oxidoreductase |
APAF | 3–8 | 0–2 | 0 | 0 | 0 | NTP binding, hetero-oligomerization |
12R-LO | 1 | 0–1 | 0 | 0 | 0 | Peroxidation of arachidonic acid |
15-LO | 1 | 0–1 | 0 | 0 | 0 | Peroxidation of arachidonic acid |
PTDSR/PSR | 1 | 1 | 0 | 0 | 1 | Recognition of apoptotic cells |