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Table 1 Actin-Like Protein (ALP) Family Members in Toxoplasma gondii and other Apicomplexans

From: Comparative genome analysis reveals a conserved family of actin-like proteins in apicomplexan parasites

  Toxoplasma gondii(Tg) Plasmodium falciparum(Pf) Cryptosporidium parvum(Cp) Theileria parva(Tp)
ALP Protein Gene IDa % ID to TgACT1 * E -value Pfam scoreb Gene IDa % to ID Tg ALP * E -value Pfam scoreb Gene IDa % ID to Tg ALP1 * E -value pfam scoreb Gene IDa % ID to Tg ALP1 * E -value pfam scoreb
Arp1 TgTwinScan_4250 53% 1.00 × 10 -116 492 CAD48998 63% 1.00 × 10 -145 464 EAK87959 57% 1.00 × 10 -134 437 - - - -
ALP1 AAW23163 39% 4.00 × 10 -73 295 AAN35700 49% 1.00 × 10 -104 257 EAK88581 45% 3.00 × 10 -94 292 EAN34027 39% 3.00 × 10 -84 246
ALP2a TgTwinScan_4277 27% 4.00 × 10 -05 53.4 AAN35636 20% 4.00 × 10 -22 78.4 EAL37900 c 27% 2.00 × 10 -13 85.4 EAN34250 24% 2.00 × 10 -24 67.7
ALP2b - - - - CAD51417 d    98.1 - - - - - - - -
ALP3 TgTwinScan_2515 23% 2.00 × 10 -16 80.8 CAD51025 36% 1.00 × 10 -6 - EAK89329 20% 1.00 × 10 -3 73.1 - - - -
ARP4a TgTwinScan_2909 34% 6.00 × 10 -19 114 AAN36831 36% 1.00 × 10 -24 131 EAK89417 38% 1.00 × 10 -22 250 EAN32990 27% 2.00 × 10 -38 160
ARP4b TgTwinScan_6634 27% 1.00 × 10 -33 115 - - - - - - - - EAN33438 22% 5.00 × 10 -15 61.9
ALP5a - - - - CAD51790 e    44.9 - - - - - - - -
ALP5b - - - - CAD49164 e    68.4 - - - - - - - -
ARP6 TgTwinScan_6605 20% 4.00 × 10 -08 71.1 CAD50940 40% 3.00 × 10 -23 68 EAL35517 c, d 30% 5.00 × 10 -22 91.9 EAN33600 31% 1.00 × 10 -37 84.6
ALP7a - - - - - - - - EAK88375 e    47.6 - - - -
ALP7b - - - - - - - - EAK88162 e    110 - - - -
ALP8 TgTwinScan_0463 f 25% 3.00 × 10 -25 106 - - - - - - - - - - - -
ALP9a TgTwinScan_2686 24% 0.008 46.5 - - - - - - - - - - - -
ALP9b TgTwinScan_7210    - - - - - - - - - - - - -
  1. * = BLAST2 pairwise comparison
  2. (-) = no significant match
  3. E -value from Pairwise Blast (BLAST 2 sequences)
  4. a = Gene ID obtained from http://www.ToxoDB.org, http://www.PlasmoDB.org, http://www.CryptoDB.org, and the NCBI database
  5. b = Pfam score to Pfam domain pfam00022 as determined by BLASTP comparison to the CDD NCBI database
  6. c = Cryptosporidium hominis
  7. d = Cp ortholog encoded on contig_AEE01000007 nt# 293712–294650 frame1. Translated using GENESCAN webserver
  8. e = primary family member
  9. f = entire Tg ortholog encoded by TGG_994550 nt# 296106–297827. Translated using GENESCAN webserver