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Table 1 Actin-Like Protein (ALP) Family Members in Toxoplasma gondii and other Apicomplexans

From: Comparative genome analysis reveals a conserved family of actin-like proteins in apicomplexan parasites

 

Toxoplasma gondii(Tg)

Plasmodium falciparum(Pf)

Cryptosporidium parvum(Cp)

Theileria parva(Tp)

ALP Protein

Gene IDa

% ID to TgACT1 *

E -value

Pfam scoreb

Gene IDa

% to ID Tg ALP *

E -value

Pfam scoreb

Gene IDa

% ID to Tg ALP1 *

E -value

pfam scoreb

Gene IDa

% ID to Tg ALP1 *

E -value

pfam scoreb

Arp1

TgTwinScan_4250

53%

1.00 × 10 -116

492

CAD48998

63%

1.00 × 10 -145

464

EAK87959

57%

1.00 × 10 -134

437

-

-

-

-

ALP1

AAW23163

39%

4.00 × 10 -73

295

AAN35700

49%

1.00 × 10 -104

257

EAK88581

45%

3.00 × 10 -94

292

EAN34027

39%

3.00 × 10 -84

246

ALP2a

TgTwinScan_4277

27%

4.00 × 10 -05

53.4

AAN35636

20%

4.00 × 10 -22

78.4

EAL37900 c

27%

2.00 × 10 -13

85.4

EAN34250

24%

2.00 × 10 -24

67.7

ALP2b

-

-

-

-

CAD51417 d

  

98.1

-

-

-

-

-

-

-

-

ALP3

TgTwinScan_2515

23%

2.00 × 10 -16

80.8

CAD51025

36%

1.00 × 10 -6

-

EAK89329

20%

1.00 × 10 -3

73.1

-

-

-

-

ARP4a

TgTwinScan_2909

34%

6.00 × 10 -19

114

AAN36831

36%

1.00 × 10 -24

131

EAK89417

38%

1.00 × 10 -22

250

EAN32990

27%

2.00 × 10 -38

160

ARP4b

TgTwinScan_6634

27%

1.00 × 10 -33

115

-

-

-

-

-

-

-

-

EAN33438

22%

5.00 × 10 -15

61.9

ALP5a

-

-

-

-

CAD51790 e

  

44.9

-

-

-

-

-

-

-

-

ALP5b

-

-

-

-

CAD49164 e

  

68.4

-

-

-

-

-

-

-

-

ARP6

TgTwinScan_6605

20%

4.00 × 10 -08

71.1

CAD50940

40%

3.00 × 10 -23

68

EAL35517 c, d

30%

5.00 × 10 -22

91.9

EAN33600

31%

1.00 × 10 -37

84.6

ALP7a

-

-

-

-

-

-

-

-

EAK88375 e

  

47.6

-

-

-

-

ALP7b

-

-

-

-

-

-

-

-

EAK88162 e

  

110

-

-

-

-

ALP8

TgTwinScan_0463 f

25%

3.00 × 10 -25

106

-

-

-

-

-

-

-

-

-

-

-

-

ALP9a

TgTwinScan_2686

24%

0.008

46.5

-

-

-

-

-

-

-

-

-

-

-

-

ALP9b

TgTwinScan_7210

  

-

-

-

-

-

-

-

-

-

-

-

-

-

  1. * = BLAST2 pairwise comparison
  2. (-) = no significant match
  3. E -value from Pairwise Blast (BLAST 2 sequences)
  4. a = Gene ID obtained from http://www.ToxoDB.org, http://www.PlasmoDB.org, http://www.CryptoDB.org, and the NCBI database
  5. b = Pfam score to Pfam domain pfam00022 as determined by BLASTP comparison to the CDD NCBI database
  6. c = Cryptosporidium hominis
  7. d = Cp ortholog encoded on contig_AEE01000007 nt# 293712–294650 frame1. Translated using GENESCAN webserver
  8. e = primary family member
  9. f = entire Tg ortholog encoded by TGG_994550 nt# 296106–297827. Translated using GENESCAN webserver