Comparative genome analysis reveals a conserved family of actin-like proteins in apicomplexan parasites

BMC Genomics

Table 4 Conserved Arp2/3 Complex Subunits in Apicomplexans

	*Toxoplasma gondii*(Tg)			*Plasmodium falciparum*(Pf)			*Cryptosporidium parvum*(Cp)			*Theileria parva*(Tp)
Arp2/3 complex subunit	Tg candidate^a	Top Match^b	E -value ^c	Pf candidate^a	Top Match^b	E -value ^c	Cp candidate^a	Top Match^b	E -value ^c	Tp candidate^a	Top Match^b	E -value ^c
Arp2	-	-	-	-	-	-	-	-	-	-	-	-
Arp3	-	-	-	-	-	-	-	-	-	-	-	-
ARPC1/ p41 ^d	-	-	-	AAN35779	SpARPC1	0.002	EAK89688	MmARPC1	1.00 × 10 ^-11	-	-	-
ARPC2/p34 ^e	-	-	-	-	-	-	-	-	-	-	-	-
ARPC3/ p21 ^f	-	-	-	-	-	-	-	-	-	-	-	-
ARPC4/ p20 ^g	-	-	-	-	-	-	EAK89016	OsARPC4	4.00 × 10 ^-11	-	-	-
ARPC5/ p16 ^h	-	-	-	-	-	-	-	-	-	-	-	-

(-) = no significant match
a = protein ID of candidate apicomplexan protein
b = identifying protein found in reciprocal BLASTP search of the NCBI database using the apicomplexan candidate as query
c = E -value of the top match identifying protein in comparison to the apicomplexan candidate
d = protein sequences used to identify apicomplexan candidates : Hs Q92747, Dm CAB38634, Sc P38328, At AAO42862, Dd AAC99777, Tc EAN83660
e = protein sequences used to identify apicomplexan candidates : Hs NP_690601, Dm Q9VIM5, Sc NP_014433, At AAM60850, Dd AAC99778, Tc EAN93128
f = protein sequences used to identify apicomplexan candidates : Hs AAH67747, Dm NP_013474, Sc NP_013474, At AAM61177, Dd AAC99779, Tc EAN89964
g = proteins used to obtain apicomplexan candidates : Hs AAB64192, Dm AAF52346, Sc NP_012912, Dd AAC99780, Tc XP_810627
h = protein sequences used to identify apicomplexan candidates : Hs NP_005708, Dm NP_608693, Sc P40518, Dd AAC99781, Tc EAN80710
At = Arabidopsis thaliana, Dd = Dictyostelium discoideum, Dm = Drosophila melanogaster, Hs = Homo sapiens, Mm = Mus musculus, Os = Oryza sativa, Sc = Saccharomyces cerevisiae, Sp = Strongylocentrotus purpuratus, Tc = Trypanosoma cruzi

ISSN: 1471-2164