Table 1 Examples of multimodular E. coli proteins.

thr A

b0002_1

1

461

e

aspartokinase I, threonine sensitive

thr A

b0002_2

464

820

e

homoserine dehydrogenase I, threonine sensitive

rib D

b0414_1

1

143

e

diaminohydroxyphosphoribosylaminopyrimidine deaminase

rib D

b0414_2

147

366

e

5-amino-6-(5-phosphoribosylamino) uracil reductase

put A

b1014_1

1

569

e

bifunctional: transcriptional repressor (N-terminal); proline dehydrogenase, FAD-binding (C-terminal)

put A

b1014_2

618

1320

e

pyrroline-5-carboxylate dehydrogenase

adh E

b1241_1

1

400

e

acetaldehyde-CoA dehydrogenase

adh E

b1241_2

449

891

e

iron-dependent alcohol dehydrogenase

thi P

b0067_1

1

274

t

thiamin transport protein (ABC superfamily, membrane)

thi P

b0067_2

285

536

t

thiamin transport protein (ABC superfamily, membrane)

mdl A

b0448_1

1

310

pt

putative transport protein, multidrug resistance-like (ABC superfamily, membrane)

mdl A

b0448_2

314

590

pt

putative transport protein, multidrug resistance-like (ABC superfamily, ATP_bind)

mod F

b0760_1

1

260

t

molybdenum transport protein (ABC superfamily, ATP_bind)

mod F

b0760_2

261

490

t

molybdenum transport protein (ABC superfamily, ATP_bind)

hrs A

b0731_1

1

178

t

PTS family enzyme IIA, induction of ompC

hrs A

b0731_2

186

454

t

PTS family enzyme IIB, induction of ompC

hrs A

b0731_3

456

628

t

PTS family enzyme IIC, induction of ompC

ato C

b2220_1

1

125

r

response regulator

ato C

b2220_2

145

461

r

sigma54 interaction module of response regulator (EBP family)

evgS

b2370_1

1

935

e

histidine kinase of hybrid sensory kinase

evgS

b2370_2

953

1197

r

response regulator of hybrid sensory histidine kinase

gln G

b3868_1

1

120

r

response regulator, two-component regulator with GlnL, nitrogen regulation

gln G

b3868_2

139

469

r

sigma54 interaction module of response regulator (EBP family)

kef A

b0465_1

1

779

o

unknown function module of mechanosensitive channel

kef A

b0465_2

780

1120

t

mechanosensitive channel (MscS family)

arg A

b2818_1

1

293

o

acetylglutamate kinase homolog (inactive)

arg A

b2818_2

298

442

e

N-alpha-acetylglutamate synthase (amino acid acetyltransferase)

ydc R

b1439_1

1

117

pr

putative transcriptional regulator (GntR family)

ydc R

b1439_2

118

468

pe

putative amino transferase

rnf C

b1629_1

1

448

pc

Fe-S binding module of electron transport protein

rnf C

b1629_2

450

740

o

unknown function module of electron transport protein