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Table 2 Differentially expressed genes from three analyses. ANOVA of xenograft data vs parental cell lines found 149 differential genes (designated ' Ap'), Linear discriminant analysis found 54 genes (designated 'LD') and ANOVA of individual xenograft tumors yielded a consensus of 12 genes (designated 'Ai'). For each gene, its presence is denoted by '1' and its absence noted by '0'. The maximum MANOVA Pvalue is reported along with the aggregate ratio (designated by 'R'). For genes with multiple independent probes, the probe reporting the maximum Pvalue is shown. Seven genes common to all three lists are in bold text.

From: Expression analysis of secreted and cell surface genes of five transformed human cell lines and derivative xenograft tumors

Ap LD Ai Gene Pval R
1 1 1 LAMB3 0.001 1.9
1 1 1 ANGPTL4 0.001 2.1
1 1 1 COL1A1 0.001 3.6
1 1 1 PCDHB9 0.001 4.0
1 1 1 GPR57 0.001 5.7
1 1 1 GP2 0.001 5.7
1 1 1 PTGER3 0.001 6.4
1 1 0 KITLG 0.001 0.4
1 1 0 RAP2B 0.001 0.4
1 1 0 COL5A1 0.237 1.0
1 1 0 SEPP1 0.054 1.0
1 1 0 CXCL1 0.3 1.1
1 1 0 TNC 0.001 1.3
1 1 0 LTBP1 0.009 1.3
1 1 0 PRSS11 0.001 1.3
1 1 0 FN1 0.008 1.4
1 1 0 FZD1 0.019 1.4
1 1 0 SPP1 1 1.5
1 1 0 IGFBP7 0.001 1.7
1 1 0 RNASE4 0.008 1.9
1 1 0 CHODL 0.003 2.1
1 1 0 NOV 0.003 2.2
1 1 0 COL12A1 0.001 2.2
1 1 0 MAGP2 0.001 2.6
1 1 0 GPR23 0.574 3.0
1 1 0 TLL1 0.001 3.2
1 1 0 GPR44 0.069 3.6
1 1 0 MGC2376 0.001 4.7
1 1 0 NPY1R 0.183 5.2
1 0 1 EMP3 0.004 0.5
1 0 1 HLA-A 0.001 0.6
1 0 1 GNAO1 0.001 2.5
1 0 0 CCR5 0.001 0.2
1 0 0 C20orf52 0.001 0.4
1 0 0 SORCS3 0.001 0.4
1 0 0 PF4 0.005 0.4
1 0 0 SPINK2 0.001 0.4
1 0 0 IGSF6 0.008 0.4
1 0 0 GPR110 0.001 0.5
1 0 0 OR1J5 0.001 0.5
1 0 0 BGLAP 0.001 0.5
1 0 0 GALR2 0.001 0.5
1 0 0 HCN2 0.001 0.5
1 0 0 CD81 0.001 0.5
1 0 0 OGFR 0.001 0.5
1 0 0 GPR6 0.001 0.5
1 0 0 OMP 0.001 0.5
1 0 0 CMA1 0.001 0.5
1 0 0 DKFZP564DO 0.001 0.6
1 0 0 CHRM1 0.001 0.6
1 0 0 PYY 0.001 0.6
1 0 0 FGF19 0.004 0.6
1 0 0 AGTR2 0.047 0.6
1 0 0 SSTR3 0.001 0.6
1 0 0 TMPO 0.001 0.6
1 0 0 TAS2R16 0.003 0.6
1 0 0 ADORA2B 0.003 0.6
1 0 0 GPR10 0.001 0.6
1 0 0 ADCYAP1R1 0.001 0.6
1 0 0 OR1F10 0.001 0.6
1 0 0 HDGF 0.001 0.6
1 0 0 CD151 0.001 0.6
1 0 0 PDAP1 0.001 0.7
1 0 0 A1BG 0.001 0.7
1 0 0 LIPF 0.001 0.7
1 0 0 PBEF 0.001 0.7
1 0 0 ART-4 0.034 0.7
1 0 0 C1QTNF3 0.029 0.7
1 0 0 SLC39A4 0.022 0.7
1 0 0 IFNGR2 0.001 0.8
1 0 0 ENT3 0.001 0.8
1 0 0 SERPINC1 0.001 0.8
1 0 0 NRP1 0.006 0.8
1 0 0 CACNA1H 0.011 0.8
1 0 0 CD44 0.001 0.8
1 0 0 STC2 0.018 0.8
1 0 0 DLK1 0.064 0.8
1 0 0 F2R 0.388 0.8
1 0 0 EMP2 0.001 0.8
1 0 0 HBE1 0.003 0.8
1 0 0 BSG 0.003 0.8
1 0 0 GPR80 0.001 0.8
1 0 0 APOB48R 0.016 0.8
1 0 0 AMELY 0.001 0.8
1 0 0 IL26 0.006 0.8
1 0 0 TRPM5 0.001 0.8
1 0 0 ENSA 0.001 0.8
1 0 0 OR1F1 0.001 0.8
1 0 0 GP3ST 0.001 0.8
1 0 0 BDNF 0.001 0.9
1 0 0 PLXN3 0.005 0.9
1 0 0 APMCF1 0.134 0.9
1 0 0 SCAMP1 0.001 0.9
1 0 0 PALMD 0.001 0.9
1 0 0 MMP8 0.02 0.9
1 0 0 MFAP3 0.004 0.9
1 0 0 SPAG11 0.001 0.9
1 0 0 A2M 0.031 0.9
1 0 0 NET-2 0.092 0.9
1 0 0 CXCL11 0.001 1.0
1 0 0 KLRB1 0.003 1.0
1 0 0 TF 0.988 1.0
1 0 0 COL14A1 0.001 1.0
1 0 0 IL7 0.002 1.1
1 0 0 COL9A1 0.001 1.1
1 0 0 CCR4 0.001 1.1
1 0 0 FPR1 0.034 1.1
1 0 0 FAP 0.001 1.2
1 0 0 OPCML 0.001 1.2
1 0 0 GPR145 0.001 1.2
1 0 0 GFRA3 0.001 1.2
1 0 0 EDN3 0.001 1.2
1 0 0 IL12B 0.043 1.3
1 0 0 CXCR4 0.026 1.3
1 0 0 PCSK5 0.427 1.3
1 0 0 NID2 0.168 1.3
1 0 0 ITGA4 0.73 1.3
1 0 0 KIAA1870 0.016 1.3
1 0 0 FBLN5 0.001 1.4
1 0 0 TRPV2 0.001 1.4
1 0 0 FGF23 0.119 1.4
1 0 0 TEM5 0.001 1.4
1 0 0 CR1 0.008 1.4
1 0 0 GPA33 0.001 1.4
1 0 0 CLCA4 0.001 1.4
1 0 0 TIMP3 0.006 1.4
1 0 0 MMP10 0.001 1.4
1 0 0 FUT8 0.197 1.4
1 0 0 FIBL-6 0.001 1.4
1 0 0 V1RL1 0.001 1.5
1 0 0 EBI2 0.003 1.5
1 0 0 ADAM28 0.001 1.5
1 0 0 GPLD1 0.008 1.5
1 0 0 CP 0.003 1.5
1 0 0 EPHA3 0.003 1.5
1 0 0 KLK11 0.001 1.6
1 0 0 OR7A17 0.001 1.6
1 0 0 IFI27 0.001 1.7
1 0 0 RNASE6 0.003 1.7
1 0 0 SELPLG 0.001 1.7
1 0 0 CST7 0.092 1.7
1 0 0 LEC3 0.001 1.7
1 0 0 TSHR 0.001 2.1
1 0 0 MC2R 0.001 2.1
1 0 0 SV2 0.001 2.1
1 0 0 SERPINA4 0.001 2.1
1 0 0 ANGPT2 0.003 2.2
1 0 0 LOC84664 0.008 2.3
1 0 0 RNASE1 0.001 2.9
0 1 1 HAS1 1 0.3
0 1 0 SLC16A8 1 0.4
0 1 0 CD164 1 1.0
0 1 0 FSTL1 1 1.0
0 1 0 IL8 1 1.0
0 1 0 KTN1 1 1.0
0 1 0 RBP4 1 1.1
0 1 0 COL5A2 1 1.1
0 1 0 TSPAN-3 1 1.1
0 1 0 CD63 1 1.1
0 1 0 IGFBP3 1 1.1
0 1 0 PLEC1 1 1.1
0 1 0 CXCL2 1 1.2
0 1 0 GPR48 1 1.2
0 1 0 FLJ20559 1 1.2
0 1 0 LAMB1 1 1.3
0 1 0 COL4A1 0.994 1.3
0 1 0 TFPI2 1 1.4
0 1 0 ESR1 0.996 1.5
0 1 0 SLC11A3 0.999 1.6
0 1 0 EFNA1 1 1.6
0 1 0 KLK13 1 2.5
0 1 0 AB065858 1 3.1
0 1 0 MMP7 0.987 3.4
0 1 0 INHBB 1 3.5
0 0 1 PI3 1 0.4