Skip to main content

Table 3 Significance levels for the main effects, two-way and three way interactions of MMU2 speed congenic donor region (DR), HG genotype (HG) (+/+ or hg/hg) and sex for selected traits

From: Genome-wide isolation of growth and obesity QTL using mouse speed congenic strains

Donor region (DR)a 6WK 9WK G26 G29 NA TF AI
Proximal (2P)        
DR <.0001 <.0001 <.0001 <.0001 <.0001 <.0001 0.0079
HG <.0001 <.0001 <.0001 <.0001 <.0001 <.0001 <.0001
Sex <.0001 <.0001 <.0001 <.0001 <.0001 <.0001 0.9840
DR*HG <.0001 0.0094 <.0001 0.0181 <.0001 0.0004 0.0183
DR*sex 0.0287 0.4783 0.0328 0.5938 0.0081 0.8780 0.5218
DR*HG*Sex 0.4092 0.4206 0.6957 0.0882 0.1563 0.1618 0.0219
Proximal middle (2PM)        
DR <.0001 <.0001 <.0001 <.0001 <.0001 <.0001 <.0001
HG <.0001 <.0001 <.0001 <.0001 <.0001 <.0001 <.0001
Sex <.0001 <.0001 <.0001 <.0001 <.0001 <.0001 0.7248
DR*HG 0.7101 0.4667 0.1277 0.1110 0.7375 0.0026 0.0065
DR*sex 0.1441 0.3947 0.1095 0.4198 0.0104 0.9323 0.6994
DR*HG*Sex 0.9437 0.2294 0.5748 0.0780 0.7697 0.0060 0.0002
Middle (2M)        
DR 0.007 <.0001 0.0234 0.0002 0.0006 0.1703 0.9707
HG <.0001 <.0001 <.0001 <.0001 <.0001 <.0001 <.0001
Sex <.0001 <.0001 <.0001 <.0001 <.0001 <.0001 0.0064
DR*HG 0.0057 0.0563 0.1875 0.6072 0.4329 0.3437 0.0256
DR*sex 0.6968 0.0089 0.8356 0.0207 0.5162 0.1460 0.0437
DR*HG*Sex 0.6205 0.1309 0.6500 0.0656 0.6704 0.0035 0.0004
  1. 6WK, weight at 6 weeks of age; 9WK, weight at 9 weeks of age; G26, weight gain from 2 to 6 weeks of age; G29, weight gain from 2 to 9 weeks of age; NA, nasal-anal body length; TF, total fat pad weight and AI, adiposity index. Significant effects after a Bonferroni correction (critical P < 0.0071) are in bold.
  2. a The distal (2D) donor region was not analyzed.