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Table 2 Direct interactions between LET-756 (DB) and clones derived from the ORFeome library. A) clones detected in the screening of the C. elegans libraries; B) orthologs of clones detected in the screening of the human placenta library; C) orthologs of known mammalian FGF interactors.

From: Direct and heterologous approaches to identify the LET-756/FGF interactome

  Interactors (AD) LET-756 (DB)
   LacZ 3-AT URA
A RPS-16 +/- ++ -
  PAL-1 ++ + -
  DAF-21 - +* -
  COL-129 +/- + -
  SKR-2 +/- +/- -
  C15C6.2 +/- + -
B KIN-10 (CSNK2B, CK2β) +/- + -
  KIN-3 (CSNK2A, CK2α) - + -
  HSP-6 (HSPA9B, mortalin) - + -
  F14E5.2 (GLG1, CFR) - +/- -
  C18A3.3 (EBNA1BP2, NoBP) - +/- -
  RPL-6 (RPL6) +/- + -
C FTT-1/PAR-5 (YWHAB, 14-3-3β) +/- + -
  FTT-2 (YWHAB, 14-3-3β) +/- + -
  ZYX-1a, ZYX-1b (ZN420) - - -
  1. *: 3-AT concentration allowing yeast growth was 20mM except for DAF-21 where it was 40 mM