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Table 5 C. elegans orthologous genes of known human FGF interactors.

From: Direct and heterologous approaches to identify the LET-756/FGF interactome

FGF

Interactor

C. elegans or human orthologs

FGF1

HSPA9B (Stress-70 protein, mortalin) [39]

hsp-6 (C37H5.8)

FGF1

NP_060979.2 (PRO1855, LOC55379, ribosome-binding protein p34, RBP34*) [39]

F56A8.3

FGF1

LDL (Low density lipoproteins) [40]

-

FGF1

S100A13 (Calcium binding protein S100A13) [41]

-

FGF1

SYT1 (Synaptotagmin-1) [5]

snt-1 (F31E8.2)

FGF1

FIBP (FGF-1 intracellular binding protein) [4]

-

FGF1 and FGF2

FGFBP1 (Fibroblast growth factor binding protein 1) [42]

-

FGF1 and FGF2

CSNK2A (Casein Kinase II, catalytic subunit α) [43]

kin-3 ( B0205.7)

FGF2

CSNK2B (Casein Kinase II, regulatory subunit β) [9]

kin-10 (T01G9.6b)

FGF2

RPL6 (Large ribosomal subunit L6) [36]

rpl-6 (R151.3)

FGF2

RPS19 (40S ribosomal protein S19) [37]

rps-19 (T05F1.3)

FGF2

CEP57 (Translokin, Centrosomal protein of 57 kDa, Proliferation-inducing protein 8, PIG8) [44]

-

FGF2

SMN1 (Survival motor neuron protein) [45, 46]

smn-1 (C41G7.1)

FGF2

FGA/FGB/FGG (Fibrinogen, alpha/beta/gamma polypeptides) [12, 47]

-

FGF2

FN1 (Fibstatin, fragment of fibronectin) [11]

C56C10.4

FGF2

API5 (Apoptosis inhibitor 5, Fibroblast growth factor 2-interacting factor, FIF) [48]

-

FGF2

SF3A2 (Splicing factor 3A subunit 2) [10]

F11A10.2

FGF2

PTX3 (Long pentraxin 3) [49]

-

FGF2

PF4 (CXC chemokine platelet factor 4) [50]

-

FGF1, FGF2, FGF3, FGF4

GLG1 (Golgi apparatus protein 1 precursor, Cysteine-rich fibroblast growth factor receptor, CFR-1) [6,7]

F14E5.2

FGF3

EBNA1BP2 (rRNA processing protein EBP2, Nucleolar Binding Protein, NoBP) [51]

C18A3.3

FGF11-14

MAPK8IP2 (Islet-brain-2, JNK MAP kinase scaffold protein 2) [52]

jip-1 (F56D12.4)

EGL-17

LRP-1 (Low-density lipoprotein Receptor Related, F29D11.1) [8]

lrp-1

EGL-17

LRP-2 (Low-density lipoprotein Receptor Related, T21E3.3) [8]

lrp-2

EGL-17

DAB-1 (Drosophila disabled homolog, M110.5) [8]

dab-1/dab-2

  1. - No approved gene name