Distinct patterns of alterations in gene expression produced by mouse scrapie strains ME7, 22L, and RML-Chandler. In this Cluster and TreeView representation of genes that differed significantly between strains, sample information is listed across the top. Each scrapie-infected mouse was compared to each of two mock-infected mice resulting in four hybridizations per strain (1a–4b). Replicate results are indicated as 1b–4b. GenBank accession numbers and gene symbols are indicated. Note the distinct patterns of altered gene expression between the three strains.