Table 7 Differentially expressed candidate genes from microarray experiments mapped in silico to autism susceptibility genes and QTL
Candidate gene | Genbank # | Physical Location | Reported closely mapped autism candidate genes or QTL* | Ref |
|---|---|---|---|---|
ASS | AA676405 | chr9 (130,349,862–130,406,214) | dopamine beta-hydroxylase (9q34) | 77 |
CHL1 | H15267 | chr3 (423,533–426,095) | KIAA0121 (3p25.2) | 75 |
IL6R-beta, gp130 | T61343 | chr5 (55,267,950–55,272,766) | Language QTL chr5:40(0–67) | 76 |
IL6ST | AA406546 | chr5 (55,271,809–55,272,305) | Language QTL chr5:40(0–67) | 76 |
DAPK1 | AI371096 | chr9 (87,552,642–87,553,099) |  |  |
FLAP, ALOX5AP | T49652 | chr13 (30,207,643–30,236,962) | AUTS3 (13q14-22), HTR2A-2 (serotonin recep. 2A) (13q14-21) | 71, 72 |
ITGB7 | AI380522 | chr12 (51,871,361–51,887,333) | arginine vasopressin receptor 1A (12q14-15) | 69 |
EGR2 | AA446027 | chr10 (64,241,755–64,246,081) | Language QTL chr10:107(72–126); HTR-7 | 76 |
ROBO1 | AA173755 | chr3 (78,729,082–78,729,496) |  |  |