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Table 1 Gene ontology classification of the HCC differentially expressed genes

From: Differentially profiling the low-expression transcriptomes of human hepatoma using a novel SSH/microarray approach

Up-regulated genes*

Down-regulated genes*

P-value

 

Cell cycle

19

4

0.052

Regulation of apoptosis

8

1

0.121

Transcription & regulation of transcription

44

13

0.040

Signal transduction

48

24

0.777

Cell organizaiton & biogenesis

28

9

0.109

Purine & pyrimidine metabolism

80

26

0.009

Protein metabolism

89

27

0.002

Nuclear ©

89

26

0.001

Chromosome ©

8

3

0.432

Cytoskeleton ©

18

5

0.128

Ubiquitin ligase complex ©

7

1

0.170

Complement & coagulation cascades

0

11

0.000

Response to wounding

4

12

0.011

Defense response

16

24

0.000

Response to external biotic stimuli

10

15

0.007

Immune response

14

21

0.001

Cell ion homeostasis

1

5

0.021

Microsome ©

2

6

0.442

Peroxisome ©

1

4

0.051

Extra-cellular space ©

4

15

0.000

  1. *Based on 360 and 202 informative up- and down-regulated genes identified using the SSH/microarray in HCC.
  2. © cellular components, based on 207 and 110 informative up- and down-regulated genes in human HCC, respectively.
  3. P value was determined by Fisher's exact test.
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BMC Genomics

ISSN: 1471-2164

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