Skip to main content

Table 8 The expression of S. ratti genes with and without significant alignment to C. elegans genes with RNAi-knockdown phenotypes.

From: A microarray analysis of gene expression in the free-living stages of the parasitic nematode Strongyloides ratti

C. elegans RNAi phenotype

BLAST alignment1

Expression2

p3

Growth

481 alignments

L1-up (1.18)

0.0001

 

1,422 no alignment

iL3-up (1.12)

 

Larval arrest

342 alignments

L1-up (1.26)

0.0001

 

1,561 no alignment

iL3-up (1.10)

 

Morphology

272 alignments

L1-up (1.22)

0.001

 

1,631 no alignment

iL3-up (1.09)

 

Movement

187 alignments

L1-up (1.17)

0.01

 

1,716 no alignment

iL3-up (1.06)

 

Reproduction

340 alignments

L1-up (1.16)

0.001

 

1,563 no alignment

iL3-up (1.09)

 

Total 4

1,622 alignments

L1-up (1.18)

0.00001

 

281 no alignment

iL3-up (1.16)

 
  1. 1Number of S. ratti ESTs with or without significant BLAST alignment to C. elegans genes with RNAi phenotypes.
  2. 2The direction of the difference in expression (i.e. L1- or iL3-up) and, shown in parentheses, the mean ratio of expression.
  3. 3The significance of the difference of the mean levels of expression for the ESTs with and without significant BLAST alignments.
  4. 4All RNAi phenotypes combined. Note, that 511 S. ratti ESTs had significant alignment to a C. elegans gene that had an RNAi phenotype in more than one phenotypic class.