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Table 1 Comparison of capillary MAPH and microarray MAPH of 28 normal samples and 21 CMT1A samples. The upper group of results show the mean and standard deviations for normalised data separated according to probe category and known pathology. * Medians used rather than means to reduce distortion by extreme outliers; see "Results" for further details.

From: Microarray MAPH: accurate array-based detection of relative copy number in genomic DNA

 

Capillary MAPH

Microarray MAPH

PMP22 Probes

Normal (n = 28)

CMT1A (n = 21)

Normal (n = 28)

CMT1A (n = 21)

 

Mean

SD

Mean

SD

Mean

SD

Mean

SD

PMP1A

0.986

0.081

1.490

0.183

1.000

0.082

1.411

0.195

PMP4

0.986

0.089

1.567

0.237

0.982

0.082

1.490

0.216

CMT5

0.962

0.127

1.607

0.290

0.981

0.161

1.428

0.210

CMT10

0.980

0.120

1.597

0.241

0.980

0.108

1.466

0.247

PMP2

0.994

0.075

1.449

0.131

0.991

0.073

1.450

0.117

PMP3

0.972

0.098

1.471

0.101

0.973

0.132

1.420

0.149

PMP22 Mean

0.980

0.098

1.530

0.197

0.985

0.106

1.444

0.189

 

Capillary MAPH

Microarray MAPH

Autosomal Probes

Normal (n = 28)

CMT1A (n = 21)

Normal (n = 28)

CMT1A (n = 21)

 

Mean

SD

Mean

SD

Mean

SD

Mean

SD

ST8D2 (19p

0.966

0.087

1.002

0.093

0.991

0.106

0.936

0.109

ST8B4 (18q)

0.960

0.117

1.058

0.161

0.991

0.074

1.014

0.094

B1

1.025

0.070

0.979

0.076

1.260*

0.811

0.970

0.169

ST10b4 (7p)

0.994

0.082

0.957

0.064

1.004

0.108

0.963

0.064

Da

1.012

0.113

0.974

0.091

1.138*

0.438

1.018

0.181

ST5C3 (8p)

0.997

0.118

1.112

0.172

1.031

0.088

1.070

0.120

ST4a4 (2q)

1.000

0.057

0.975

0.078

0.992

0.060

0.973

0.089

ST11G9 (19q)

0.989

0.160

0.968

0.099

0.952

0.123

0.957

0.153

A2

0.960

0.135

1.071

0.164

1.000

0.285

1.050

0.175

Autosomal Mean

0.989

0.104

1.011

0.111

1.040

0.233

0.994

0.128

 

Male

Female

Male

Female

 

Mean

SD

Mean

SD

Mean

SD

Mean

SD

Y

0.522

0.061

0.021

0.014

0.530

0.070

0.083

0.055

X

0.482

0.077

0.952

0.424

0.555

0.107

0.930

0.312