Table 1 Poly-pu/py-rich sequence contexts of polymorphisms associated with hot spot activity in humans. Sequence contexts of the three polymorphisms associated with reduced recombination frequencies in human hot spots. The recombination-suppressing alleles are shown in lower case.
From: Association of poly-purine/poly-pyrimidine sequences with meiotic recombination hot spots
Hot Spot | References | Sequence context | Distance from hot spot mid point (bp) |
|---|---|---|---|
MS32 | [19] | (G/c)GTGGGAAGGGTGG | 151 |
NID 1 | [3, 18] | CC(C/t)CCCACCCCACCCC | 64 |
DNA 2 | [4, 16] | AGGGGGCAGCAACAGGG(A/g)GG | 166 |