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Table 2 Tetraodon nigroviridis protein genes under positive Darwinian selection with significantly lower (a) or higher (b) distance to the human ortholog than other fish species. Duplicated genes are given with rate differences between the two copies according to the relative rate test of Tajima (1993) at the 5% level with one asterisk and at the 1% level with two asterisks.

From: Many genes in fish have species-specific asymmetric rates of molecular evolution

GenBank Acc#

annotation according to human (UniGene)

duplicate rate difference

CAG12160.1

lysyl oxidase-like 1 a

0.247**

CAF89330.1

nuclear LIM interactor-interacting factor 2 a

0.120**

CAG00079.1

chloride intracellular channel 5 a

0.053*

CAG07128.1

twisted gastrulation a

-

CAF96302.1

TAFA2 a

0.014

CAF96493.1

serine/threonine protein kinase 6; aurora-A; IPL1-related kinase a

0.067**

CAG00266.1

hypothetical protein DKFZp564D0478 a

0.147*

CAF94681.1

eukaryotic translation elongation factor 1 gamma a

-

CAF96262.1

TTK protein kinase a

-

CAF91195.1

zinc finger protein 207 a

-

CAF91040.1

exosome component 7a

-

CAF87120.1

hypothetical protein FLJ10996 a

-

CAF92823.1

ubiquitin domain containing 1 a

0.128

CAF91601.1

peroxisomal lon protease a

-

CAF95463.1

hypothetical protein FLJ21156 a

-

CAF91120.1

syntaxin binding protein 1 b

0.350**

CAG08971.1

short-chain dehydrogenase/reductase b

-

CAG13862.1

exostosin 1 b

0.074