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Table 4 Danio rerio genes under positive Darwinian selection with significantly lower (a) or higher (b) distance to the human ortholog than other fish species. Duplicated genes are given with rate differences between the two copies according to the relative rate test of Tajima (1993) at the 5% level with one asterisk and at the 1% level with two asterisks. Known gene symbols according to ZFIN are also provided.

From: Many genes in fish have species-specific asymmetric rates of molecular evolution

Ensembl Acc# annotation according to human (UniGene) duplicate rate difference ZFIN
ENSDARP00000003385 ankyrin repeat domain 28 a 0.285** ankrd
ENSDARP00000024204 vesicle-associated membrane protein A isoform 2 a - vapa
ENSDARP00000006783 cofilin 2 a 0.078* cfl2
ENSDARP00000026380 KIAA0073 protein a - -
ENSDARP00000039499 haloacid dehalogenase-like hydrolase domain containing 2 a - -
ENSDARP00000005886 arsenate resistance protein ARS2 isoform b a - ars2
ENSDARP00000049098 thyroid hormone receptor interactor 13 a - trip11
ENSDARP00000010419 DnaJ subfamily A member 2 a 0.135 dnaja2
ENSDARP00000048880 gamma-glutamyl Carboxylase a - ggcx
ENSDARP00000025803 SEC14 (S. cerevisiae)-like 1 a 0.114 sec14l1
ENSDARP00000001039 hypothetical protein MGC10882 a - -
ENSDARP00000038616 glutaryl-Coenzyme A dehydrogenase isoform a precursor a 0.083 gcdh
ENSDARP00000024124 activin A type II receptor precursor a 0.057** acvr2a
ENSDARP00000025487 DKFZP434B168 a - dkfzp434b168
ENSDARP00000024082 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP a - atic
ENSDARP00000038219 roundabout 1 isoform a a 0.276* robo1
ENSDARP00000008117 HIRA interacting protein 5 a - -
ENSDARP00000026984 beta catenin-like 1 a - -
ENSDARP00000046992 carbohydrate (chondroitin) synthase 1 a - chys1
ENSDARP00000016016 phosphatidylserine decarboxylase a - -
ENSDARP00000023471 ADP-ribosylation factor-like 6 interacting protein a - arl6ip
ENSDARP00000002978 aspartate aminotransferase 1 a 0.015** -
ENSDARP00000016111 ADP-ribosylation factor 4-like a 0.032** arl4
ENSDARP00000018086 androgen-induced 1 a - aig1
ENSDARP00000015026 signal recognition particle 72 kDa a - wu:fi03d11
ENSDARP00000038278 cytidine deaminase a - aicda
ENSDARP00000006977 ankyrin repeat domain 10 b 0.211 ankrd10
ENSDARP00000009789 chromobox homolog 3 HP1 gamma a 0.009** cbx
ENSDARP00000016540 RAB25 a 0.170* rab